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When working through the problems in the PDF, always print the spectra, draw the fragments in pencil, and use colored highlighters for HMBC correlations. The physical act of tracing connections trains the brain to "see" the invisible bonds between atoms. This write-up synthesizes the core principles and methodologies found in standard educational PDFs on 2D NMR structure elucidation, such as those by Field, Sternhell, and Kalinowski, or problem sets from university courses.
When working through the problems in the PDF, always print the spectra, draw the fragments in pencil, and use colored highlighters for HMBC correlations. The physical act of tracing connections trains the brain to "see" the invisible bonds between atoms. This write-up synthesizes the core principles and methodologies found in standard educational PDFs on 2D NMR structure elucidation, such as those by Field, Sternhell, and Kalinowski, or problem sets from university courses.