The short answer is Fusion 360 is not a traditional offline desktop application like SolidWorks or older versions of AutoCAD. However, Autodesk has built a robust "Offline Mode" for specific scenarios.
Before you travel offline, use the "Export" function to save a local copy of your designs as an .f3d or .step file onto your hard drive. If offline mode fails, you still have a master backup. fusion 360 offline
Autodesk Fusion 360 is widely known as a "cloud-powered" 3D CAD, CAM, and CAE tool. For engineers and designers working in remote areas, on airplanes, or in facilities with unstable internet, the obvious question arises: Can I actually use Fusion 360 when I am offline? The short answer is Fusion 360 is not